CELLPURICS
CELLPURICS
Exploratory general, genetic and in vitro toxicology
Ocular PD
Chronic/ subchronic toxicology
→ 13 weeks & 26/39 weeks
Carcinogenicity study
(2 year rat/mouse, and 26 weeks rasH2 transgenic mice)
Reproductive toxicology (Seg I, Seg II, SegIII)
AE investigative type studies
General toxicology (rodent, rabbit, dog, NHP, minipig)
: 14 days & 28 days
Genetic and in vitro toxicology
: Genetic Toxicology
(Ames, chromosomal aberration, micronucleus, MLA, Comet)
: In Vitro Electrophysiology (hERG)
: In Vitro Phototoxicity (3T3 NRU Phototox)Safety pharmacology
Safety pharmacology
: Screening
: Core battery
Developmental and reproductive toxicology
: Seg1 Fertility (rat)
: Seg2 Emboyo-fetal developmental (rat & rabbit)
: Seg3 Prenatal and postnatal developmental (rat)
: Seg4 Multi-generation
Local tolerance
Method transfer, development, validation and sample analysis
Method transfer, development, validation and sample analysis
Immunohistochemistry
Flow cytometry
Immunochemistry
Tissue cross reactivity (rat, dog, monkey, human)
Immunogenicity or ADA assay
Bioanalysis
Biomarkers
RT-qPCR assay
SEND data sets available within 10 working days of report date
